Brigitte's on the run from Bailey Downs, and she tries to prevent what happened to her sister, Ginger, from happening to her by shooting up with monkshood. Eventually she collapses and the police that find assume the monkshood is an illegal drug, and she is sent to rehab. She is deprived of the only thing that will stop her from turning into a beast and killing everyone and everything in her way. She meets a girl who is quiet and not well-liked, and much like herself, by the name of Ghost that helps her deal with her new problem and to escape the werewolf curse.

A guy who danced with what could be the girl of his dreams at a costume ball only has one hint at her identity: the Zune she left behind as she rushed home in order to make her curfew. And with a once-in-a-lifetime opportunity in front of him, he sets out to find his masked beauty.

A tale told over four seasons, starting in autumn when Juno, a 16-year-old high-school junior in Minnesota, discovers she's pregnant after one event in a chair with her best friend, Bleeker. In the waiting room of an abortion clinic, the quirky and whip-sharp Juno decides to give birth and to place the child with an adoptive couple. She finds one in the PennySaver personals, contacts them, tells her dad and step-mother, and carries on with school. The chosen parents, upscale yuppies (one of whom is cool and laid back, the other meticulous and uptight), meet Juno, sign papers, and the year unfolds. Will Juno's plan work, can she improvise, and what about Bleeker?